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Novantrone Information
Novantrone is an anti-neoplastic drug. It is referred to as an anthracenedione. It is used for the treatment of those patients who have primary progressive MS (multiple sclerosis). The drug is used to reduce the neurologic disability. The generic drug is also used to reduce the frequency of relapses. The drug acts by intercalating into the DNA (through hydrogen-bonding). Then it causes breaks in the DNA strand and cross-links. The drug also interferes with the RNA and inhibits the enzyme topoisomerase-II which is responsible for repairing and uncoiling of damaged DNAs. It is a prescription drug and cheap Novantrone can be bought from many reputed pharmacies.
Novantrone Side Effects and Precautions
Less common/ rare side effects of Mitoxantrone are fever, chills, blood in urine/ stools, decreased urination, seizures, pin-point red color spots on the skin, red eyes, sore eyes, yellowing of the eyes or the skin or swelling in the feet or lower legs. Other rare side effects of Novantrone are skin rashes, bluish skin at the site of injection or reddening/ pain at the site of injection. The drug may have some common side effects as well.
These common (and less serious) side effects of Mitoxantrone are constipation, congestion, body pain, soreness/ dryness of the throat, hair loss, back pain, irregular or no menstrual periods, headache, runny nose, sneezing, stuffy nose or swollen glands of the neck. Do not buy Novantrone and administer it, if you are hyper-sensitive to it.
Dosage Information On Novantrone
The recommended dose of Novantrone for treating MS is 12 mg/m2. It is given as IV infusion over a period of 5-15 minutes. The drug is administered once every three months. The recommended dose for hormone refractory prostate cancer is 12 mg/m2 to 14 mg/m2 given as IV infusion. It is administered once in 21 days. Discount Novantrone can be ordered from North Drug Mart, where the drug is available at a standard dosage of 2 mg/ ml.
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